| Scientific Name | Author | English Name |
|---|---|---|
| Profundulus candalarius | Hubbs, 1924 | Headwater killifish |
| Profundulus guatemalensis | (Günther, 1866) | |
| Profundulus hildebrandi | Miller, 1950 | Chiapas killifish |
| Profundulus kreiseri | Matamoros, Schaefer, Hernández & Chakrabarty, 2012 | Kreiser’s Killifish |
| Profundulus labialis | (Günther, 1866) | Largelip killifish |
| Profundulus mixtlanesis | Ornelas-García, Martínez-Ramírez & Doadrio, 2015 | |
| Profundulus oaxacae | (Meek, 1902) | |
| Profundulus portillorum | Matamoros & Schaefer, 2010 | |
| Profundulus punctatus | (Günther, 1866) | Oaxaca killifish |